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What is a CPA network? How GLP-1 offers pay and get approved

A CPA network is a company that holds deals with advertisers and pays affiliates a set amount each time a visitor completes an agreed action, such as a sale or a sign-up. You get one account, many offers and one payment. On GLP-1 telehealth offers, the action is usually a first paid order, and the brand approves your creative.

How a CPA network works

A CPA network sits between advertisers and affiliates and earns the gap between what the advertiser pays per action and what it pays you. CPA stands for cost per action (some say cost per acquisition). The network runs the tracking, the offer list, fraud checks and payments.

The three parties:

PartyWhat it doesWhat it wants
Advertiser (the brand)Sets the action it pays for, the rate and the rulesReal customers at a known cost
CPA networkSigns the brand, recruits affiliates, tracks, paysVolume and a margin on each action
Affiliate (you)Sends visitors through a tracking linkA good rate, paid on time

The network’s margin is why the same offer can pay you less through a network than direct with the brand. It’s also why a network that buys an offer from another network (a sub-network) usually pays less again. We compare the routes GLP-1 offers take in telehealth affiliate networks.

What a CPA payment is

A CPA payment is a fixed amount paid for one completed action. The offer page names the action, and only that action pays. Common models on a CPA marketing network:

  • CPA or CPS (per sale) pays on a purchase. GLP-1 telehealth offers often pay here, on a first paid order or a paid consult.
  • CPL (per lead) pays on a form or sign-up. Telehealth offers sometimes pay on a completed intake instead of a sale.
  • CPI (per install) pays on an app install.
  • Rev share pays a share of what the brand earns, sometimes on refills too.

What GLP-1 brands publish about these models is in GLP-1 affiliate commissions.

The three approvals in a CPA network

A CPA network has three approval steps, and for GLP-1 offers the last one belongs to the brand. Traffic you send before all three are in place may not pay.

Diagram of the three approvals an affiliate passes before GLP-1 traffic counts toward a payout: first the network account, decided by the network from your traffic sources, sites and track record; second the offer, decided by the network, often checking with the brand, from the traffic you plan to send; third the creative, decided by the brand through your network manager, from your claims, images, landing page and disclosure
Who decides at each approval step, and what they check, on a GLP-1 offer.
ApprovalWho decidesWhat helps you pass
Network accountThe network, often after a call with an affiliate managerNamed traffic sources, live sites or ad accounts, past results you can show
OfferThe network, often checking with the brand on regulated offersA clear plan: which traffic, which states, which angle
CreativeOn GLP-1 offers, the brand, through your managerBrand-approved claims, a disclosure, a landing page the brand has seen

The brand holds the creative step on GLP-1 offers because the ad platforms certify the brand, not you. Meta’s policy says: “Meta requires online pharmacies and telehealth providers to be actively certified with LegitScript.” Demand for that certification is rising. LegitScript reported a 101% increase in telemedicine certification applications over the past year in its September 22, 2026 release.

CPA network payment terms: hold, net terms and minimums

CPA network payment terms decide when an approved action turns into money in your account. Five terms matter, and you should get each one in writing before you send traffic.

Timeline of a CPA network payment in six steps: click through your tracking link with a sub-ID; conversion, when the brand records the paid action such as a first paid order on a GLP-1 telehealth offer; hold, while refunds, chargebacks and duplicates are checked, with the length set in the offer terms; pay period close, weekly or monthly, set in the network terms; net terms, the days after the period closes before the network pays; paid, if your balance reaches the minimum payout, otherwise it rolls into the next period. After payment, a reversal found later can be deducted from a future payout if the terms allow it
The path from click to payment, and which document sets each step.
TermWhat it meansQuestion to ask
Hold (validation)Days a conversion stays pending while the brand checks itHow long, and what gets a conversion rejected?
Pay periodHow often the network closes your balance: weekly, twice a month, monthlyWhen does the period close?
Net termsDays after the period closes before payment (“net 15” means 15 days)Is it net from period close or from brand payment?
Minimum payoutThe balance you need before the network paysWhat happens to a balance below it?
ReversalsConversions taken back after a refund or chargebackCan a reversal hit money already paid, and for how long?

Tax paperwork is part of the terms too. A US network usually asks US affiliates for a Form W-9. For tax years beginning after 2025, the IRS instructions for Form 1099-NEC set the reporting line at “$2,000 or more” in nonemployee compensation, up from $600.

On GLP-1 offers, ask how the brand’s refund policy passes down to you. Each telehealth brand sets its own refund rules, and a refunded first order can come back to you as a reversal. When an offer stops, pending conversions are a separate question, covered in why GLP-1 offers get paused.

GLP-1 telehealth offers on a CPA network

GLP-1 telehealth offers on a CPA network pay on a brand’s sale, not on a drug sale, because a licensed clinician at the brand decides on any prescription. You send visitors, and the brand handles everything after the click. Offer categories you’ll see:

  • Monthly or multi-month telehealth weight-loss plans
  • Paid consultations
  • Branded medication programs
  • Compounded medication programs, which carry their own claim rules

The audience is large. KFF’s poll published November 14, 2025 found that 18% of US adults had ever taken a GLP-1 drug and 12% were taking one. Among people who had taken one, 17% got it from an online provider or website, the channel these offers sell.

Which traffic a CPA network allows on GLP-1 offers

A CPA network passes the brand’s traffic rules to you, so the allowed list on a GLP-1 offer starts with the brand. This is how we run it for GLP-1 offers:

Traffic sourceAllowed?Why
SEO and content sitesAllowed with conditionsDisclosure next to every link; no made-up ratings or reviews
Meta (Facebook, Instagram)Allowed with conditionsBrand-approved creative only; no before-and-after images
Instagram influencersAllowed with conditionsYour own account and audience; brand-approved claims only
Google and Microsoft searchAllowed with conditionsGeneric terms only
Search ads on the brand’s nameNot allowed without written approvalCompetes with the brand’s own search ads
EmailAllowed with conditionsYour own opt-in list, CAN-SPAM compliant, copy reviewed first
NativeAllowed with conditionsPre-landers reviewed first; no fake news layouts
Coupon and deal sitesAllowed with conditionsCodes and discounts the brand approves
Incentivized or cashback trafficNot allowedVisitors with no intent to buy
Push, pop and bot trafficNot allowedLow intent and fraud risk

Our rules for publishers on GLP-1 offers

Our rules for publishers on GLP-1 offers follow the brand’s rules and the FTC’s. The FTC’s Endorsement Guides FAQ tells affiliates: “You should disclose your relationship to the retailer clearly and conspicuously on your site.” In short:

  • Affiliate disclosure next to every link, in plain words.
  • Brand-approved claims only. No weight-loss results, no before-and-after images, no prescription promises.
  • Prices and plan details exactly as they appear on the brand’s current landing page.

How brands watch for claims that break these rules is in monitoring GLP-1 affiliate ads.

How to check a CPA network before you join

The best CPA network for you is the one with a direct deal with the brand, clear terms and fair rules on reversals, so check those before you look at the rate. Networks also carry legal weight. On October 4, 2016, the FTC announced a federal appeals court ruling that held the operator of an affiliate network liable for deceptive claims its affiliates made for a weight-loss supplement, with $11.9 million to pay. The FTC wrote: “The decision is the first by a court of appeals holding the operator of an affiliate marketing network liable for deception by third-party marketers.”

Read a CPA network’s sign-up page and terms against this table before you send a click:

What to checkGood signRed flag
FeesFree to join; the network earns from the advertiserA sign-up, “activation” or training fee
Source of the offerDirect from the brand, named on requestCan’t or won’t say where the offer comes from
Creative approvalA named person and a stated turnaround“Run it and we’ll see” on a GLP-1 offer
Hold and rejectionsHold length and rejection reasons in writingConversions rejected with no reason given
Reversals after paymentA fixed window, tied to the brand’s refund rulesOpen-ended clawbacks on paid balances
PaymentPay period, net terms, minimum and method in the termsTerms only “discussed with your manager” and never written
TrackingPostbacks to your own tracker; sub-IDs for traffic labels onlyAsks you to pass names, emails or health details in sub-IDs
Compliance helpBrand claim rules and disclosure rules sent before launchNo rules until after a complaint

FAQ

What’s the difference between a CPA network and an affiliate network?

A CPA network is a type of affiliate network that pays per action. Many affiliate networks also run rev share or hybrid deals, and people use the two terms for the same thing.

What is a CPA program?

A CPA program is one advertiser’s offer that pays a fixed amount per action. A CPA network carries many such programs in one account.

Can you promote GLP-1 offers through a CPA network?

Yes, if the network carries prescription telehealth offers and you follow the brand’s rules. Some large affiliate programs exclude prescription drugs. Amazon Associates, for one, lists “prescription drugs, or any other product sold by Amazon Pharmacy” among its excluded products. Check that the “GLP-1” offers are telehealth plans and not supplements.

Sources

  1. FTC, U.S. Circuit Court Finds Operator of Affiliate Marketing Network Responsible for Deceptive Third-Party Claims Made for LeanSpa Weight-loss Supplement (October 4, 2016) · accessed
  2. FTC, FTC's Endorsement Guides: What People Are Asking · accessed
  3. IRS, Instructions for Forms 1099-MISC and 1099-NEC (Rev. December 2026; $2,000 threshold for tax years beginning after 2025) · accessed
  4. KFF Health Tracking Poll: Prescription Drug Costs, Views on Trump Administration Actions, and GLP-1 Use (November 14, 2025; 18% ever, 12% current, 17% of users from an online provider or website) · accessed
  5. LegitScript, Certification Applications Rise 59%, Led by 101% Growth in Telemedicine (September 22, 2026) · accessed
  6. Meta Transparency Center, Drugs and pharmaceuticals · accessed
  7. Amazon Associates, Program Policies (Excluded Products) · accessed
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